Microwave-assisted Synthesis of Acridine-1,8(2H,5H)-diones via a One-pot, Three Component Reaction
نویسندگان
چکیده مقاله:
A new and improved protocol for the synthesis, in good to excellent yields, of acridine-1,8(2H,5H)-diones is described, involving a one-pot, three component reaction of dimedone, arylglyoxals, and ammonium acetate in water under microwave irradiation.
منابع مشابه
A one-pot, three-component reaction for the synthesis of novel 7-arylbenzo[c]acridine-5,6-diones.
A one pot domino protocol for an efficient synthesis of 7-arylbenzo[c]acridine-5,6-diones, with a novel nucleus, has been developed by reacting 2-hydroxynaphthalene-1,4-dione, aromatic aldehydes and aromatic amines using environmentally benevolent p-toluene sulphonic acid as a catalyst. An exciting feature of this communication is the reaction mechanism that depends on the reaction solvent.
متن کاملA novel microwave-mediated one-pot synthesis of indolizines via a three-component reaction.
[reaction: see text] The microwave-mediated three-component reaction of acyl bromide, pyridine, and acetylene is catalyzed by basic alumina to give corresponding indolizines in excellent yields in a one-pot reaction.
متن کاملMicrowave-Assisted Three Component Cyclocondensation Reaction: A Facile Synthesis of Highly Functionalized Cyclohexene Derivatives
Microwave-assisted three component cyclocondensation reactions of aldehydes, amides and dienophiles in the presence of acetic anhydride and para-toluenesulfonic acid as a catalyst to afford the highly substituted cyclohexene derivatives, in relatively good yields after several minutes are reported.
متن کاملAn Efficient Synthesis of 4H-chromene Derivatives by a One-pot, Three-component Reaction
A facile and efficient one-pot, multicomponent synthesis of 4H-chromenes is reported, through the reaction of arylglyoxalmonohydrates with 1,3-diketones and malononitrile in eTEMPthanol in the presence of L-proline as a catalyst.
متن کاملMicrowave-assisted one pot three-component synthesis of some novel pyrazole scaffolds as potent anticancer agents
BACKGROUND Pyrazoles, thiazoles and 1,3,4-thiadiazoles have been reported to possess various pharmacological activities. RESULTS An efficient and a novel approach for the synthesis of some novel pyrazole based-azoles are described via multi-component reaction under controlled microwave heating conditions. The structures of the synthesized compounds were assigned on the basis of elemental anal...
متن کاملOne-Pot Multi-Component Synthesis of Dihydropyrimidinones via Biginelli Condensation
Three-component reactions have emerged as useful methods because the combinationof three components to generate new products in a single step is extremely economical,among the multi-component reactions. A green, simple, efficient, and cost-effective procedure has been carried out by the synthesis of dihydropyrimidinonesin Biginelli’s condensation of ethyl cyanoacetate, aldehyde and urea or thio...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ذخیره در منابع من قبلا به منابع من ذحیره شده{@ msg_add @}
عنوان ژورنال
دوره 36 شماره 2
صفحات 1- 6
تاریخ انتشار 2017-05-01
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023